Since the Ribosomes are often referred to as the "powerhouse" of a cell, the cell would basically shut down. And also the Ribosomes are the place where the proteins for a cell are made, so if the Ribosomes shut down, the cell won't have any proteins or energy to do all its processes.
If the ribosomes of a cell were destroyed, the cell would be unable to synthesize proteins, as ribosomes are the molecular machines responsible for translating RNA into protein. This would likely result in a halt to cellular growth and metabolism and ultimately lead to cell death. Without functioning ribosomes, for instance, liver cells would not produce essential blood proteins, which could impair immune system functionality and blood transport. Moreover, since ribosomes are partially composed of RNA, agents that damage DNA could also affect ribosomal RNA and thus inhibit protein synthesis.
If the 60S ribosomal subunit became nonfunctional due to mutation, as in the case of the scientist's experiment on a human cell line, it would predictably lead to a stall in translation, specifically after the initiation AUG codon is identified, preventing the assembly of a functional ribosome and subsequent protein synthesis.
If ribosomes in a cell are destroyed, the cell will be unable to produce proteins, leading to a breakdown of essential cellular functions. This can result in the cell's inability to survive and perform necessary roles in the body. Consequently, such damage can severely affect overall health and function of tissues and organs.
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