Which immunoglobulin class(es) can fix complement?
A. IgG only
B. IgM only
C. IgE and IgA
D. IgD only
Answer (2)
Both IgG and IgM can fix complement, which means they activate the complement system crucial for the immune response. IgM is particularly effective due to its pentameric structure, while IgG’s subclasses also have complement-fixing capability. Classes like IgE, IgA, and IgD do not fix complement. ;
Both IgG and IgM can fix complement, actively participating in the immune response, while IgE, IgA, and IgD do not activate the complement system. This makes IgG and IgM significant in fighting infections. Therefore, the correct option is not explicitly listed in the choices given, but both IgG and IgM are the relevant immunoglobulin classes.
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