The membrane potential in living cells is primarily determined by the permeability of the membrane to ions, especially potassium. A cell's leaky nature to potassium conductance is central to maintaining a negative resting potential. During the depolarization phase of an action potential, sodium influx occurs, significantly altering the membrane potential. ;
The correct answer is that the membrane potential is maintained by a membrane that is leaky to potassium conductance. This allows potassium ions to exit the cell, which helps maintain a negative resting potential. During depolarization, sodium influx occurs, temporarily altering the membrane potential positively.
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